Longevity UnmaskedLongevity Unmasked

Question 36 of 433

Is inflammation really part of heart disease?

Evidence grade (draft mapping)ARobust human trialsCObservational
Bright lab: single capped blood tube held in gloved hand by window

The short answer

Yes, and we can measure it with an inexpensive blood test called hs-CRP only when it could clarify a cardiovascular risk decision.

A 2024 study followed nearly 28,000 women for thirty years. Three simple blood tests taken once, LDL, Lp(a), and hs-CRP, predicted heart events three decades later. The inflammation marker was the strongest of the three.

We also have proof that calming inflammation helps. Low-dose colchicine, an old gout medicine, reduced heart events by about 30 percent in people with coronary disease and is now approved for that purpose. It is not for everyone, but it shows that the inflammation story is true.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ROBUST HUMAN TRIALS for selected anti-inflammatory treatment; OBSERVATIONAL for hs-CRP risk prediction.Evidence grade (draft mapping)ARobust human trialsCObservationalPart 3, Q36 · Part sources
All of Part 3

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