Question 60 of 433
What about “inflammation panels” with Lp-PLA2, MPO, and oxidized LDL?
The short answer
SKIP. hs-CRP is the only inflammation test with a role in guidelines.
These markers track with risk in studies, but a drug that lowered one of them failed in two large trials, and no study shows that measuring them changes what we do. They add $100 to $400 to a bill. Measure the fire with hs-CRP, and spend the difference on something useful.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
INSUFFICIENT CLINICAL UTILITY — Routine wellness panels: additional inflammatory markers have no established outcome advantage.Evidence grade (draft mapping)FNot demonstrated / insufficientPart 5, Q60 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.