Question 61 of 433
Should I treat a high homocysteine?
The short answer
SKIP it as a heart or longevity target. Check it only if B12 or folate deficiency is suspected.
High homocysteine is linked to heart disease, so for years doctors prescribed B vitamins to lower it. The vitamins lowered the number, and in several large trials heart attacks and deaths did not change. It is a marker, not a lever.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
ROBUST HUMAN TRIALS — Broad cardiovascular prevention: homocysteine lowering has not consistently reduced events; deficiency care is separate.Evidence grade (draft mapping)ARobust human trialsPart 5, Q61 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.