Longevity UnmaskedLongevity Unmasked

Question 396 of 433

Can common medications harm my memory?

Evidence grade (draft mapping)CObservationalARobust human trials
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The short answer

Yes. A group called anticholinergics, which includes many over-the-counter sleep aids and allergy pills, is linked to confusion and a higher risk of dementia with long-term use.

The best-known example is diphenhydramine, the ingredient in most “PM” products. Some bladder medicines, older antidepressants, and muscle relaxants are in the same family. Sedatives such as benzodiazepines add fall risk. If you are over 60, ask your doctor or pharmacist to check your list for these.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ROBUST for acute anticholinergic cognitive effects; OBSERVATIONAL for long-term dementia associations.Evidence grade (draft mapping)CObservationalARobust human trialsPart 27, Q396 · Part sources
All of Part 27

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