Longevity UnmaskedLongevity Unmasked

Question 395 of 433

Are over-the-counter painkillers safe to take regularly?

Evidence grade (draft mapping)ARobust human trials
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The short answer

Not the anti-inflammatory ones. Ibuprofen, naproxen, and similar drugs raise blood pressure, strain the kidneys, cause stomach bleeding, and increase heart attack risk with regular use.

Even occasional use should fit your conditions and other medicines. For ongoing pain, discuss the cause and options such as topical treatment, physical therapy, or an appropriate exercise program. Acetaminophen also has dose limits and liver risks; no daily analgesic is automatically safe. If you have heart disease, kidney disease, or take a blood thinner, ask before using them at all.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ROBUST SAFETY EVIDENCE — NSAID users: GI, kidney, and cardiovascular risks vary by drug, dose, and patient.Evidence grade (draft mapping)ARobust human trialsPart 27, Q395 · Part sources
All of Part 27

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