Question 249 of 433
What is GlyNAC?
The short answer
A combination of two amino acids, glycine and N-acetylcysteine, that the body uses to make glutathione, its main internal antioxidant. Results from small trials are striking and need to be repeated.
In a trial of 24 older adults at Baylor, sixteen weeks of GlyNAC improved markers of oxidative stress, inflammation, insulin resistance, walking speed, and grip strength. Twenty-four people is very few. The doses used were also large. Glycine on its own, about 3 grams before bed, has modest evidence for improving sleep quality and is inexpensive.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
SMALL HUMAN TRIAL — Older adults: GlyNAC biomarker and functional signals need independent replication.Evidence grade (draft mapping)BLimited or small human studiesPart 17, Q249 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.