Topic from the book cover

Supplements, Drugs & Technology

Part 17 · 22 questions

Supplements, Ranked by Evidence

• No supplement has been shown to extend human life.
• Test, correct what is low, and add only what has human evidence.
• Bring every bottle to your doctor once a year.

Part 18 · 10 questions

The Longevity Drugs

• Rapamycin, metformin, and senolytics are promising in animals and unproven in people.
• Biomarkers can improve while outcomes do not.
• If you want to try one, do it in a trial or with monitoring.

Part 19 · 13 questions

Repurposing Today’s Medicines for Longevity

• The best-proven “longevity drugs” already exist: they lower blood pressure and LDL.
• SGLT2 inhibitors and GLP-1 medicines extend life in people with the right conditions.
• For healthy people, metformin, rapamycin, and daily tadalafil remain unproven.

Part 20 · 33 questions

The Toy Chest: Every Drip, Device, and Gadget, Graded

• Sort every gadget onto three shelves: reasonable, pleasant, or leave it.
• Sauna has the best long-term data of any of these toys.
• IV drips, NAD infusions, cryotherapy, and soft pressure chambers are not worth the money.

Part 21 · 12 questions

The Med Spa Menu: Skin, Shape, and Sex

• Cosmetic treatments change appearance, not aging.
• Sunscreen and a prescription retinoid outperform every device.
• Ask who is holding the needle and where the product came from.

Part 22 · 23 questions

Mind, Body, and the Experimental Shelf

• Breathwork and tai chi are free and proven.
• Brain stimulation and ketamine are real treatments for depression, not wellness products.
• Decline any “stack” or “protocol” with no published trial.

Part 23 · 6 questions

The Frontier: Regenerative Medicine

• Cell reprogramming is the most important idea in the field and is just entering human testing.
• Stem cells, exosomes, and young plasma are not proven for aging.
• Legal in a state is not the same as shown to work.

Topic groupings are an editorial navigation aid, not part of the book.