Longevity UnmaskedLongevity Unmasked

Question 40 of 433

I have been told I have plaque. Is that a death sentence?

Evidence grade (draft mapping)ARobust human trials
Bright modern CT scanner room in daylight, empty

The short answer

No. Plaque can be stabilized, and with intensive treatment it can shrink. Finding it early is good fortune.

When LDL cholesterol is driven low enough, usually with a statin plus a second medicine such as ezetimibe or a PCSK9 inhibitor, imaging studies show plaque volume decreasing and the dangerous soft plaque becoming firmer and less likely to rupture. Blood pressure control, not smoking, exercise, and, for people with diabetes or obesity, the newer metabolic drugs all add protection.

I tell patients that a positive scan is not a verdict. It is a head start. The people I worry about are the ones who have plaque and do not know it.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ROBUST HUMAN TRIALS — Adults with atherosclerotic disease: lipid lowering reduces events; imaging regression is a separate outcome.Evidence grade (draft mapping)ARobust human trialsPart 3, Q40 · Part sources
All of Part 3

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