Longevity UnmaskedLongevity Unmasked

Question 330 of 433

Are psychedelic therapies available?

Empty reclining therapy chair with blanket in dim navy room

The short answer

Not yet as approved medicine in the United States, though psilocybin is close.

The FDA declined to approve MDMA-assisted therapy for trauma in 2024 and asked for more study. A psilocybin treatment for resistant depression succeeded in two late-stage trials and is being submitted to the FDA, with a decision possible in 2027. For now, legal supervised use exists only in a few state programs, such as those in Oregon and Colorado. Retreats and underground sessions carry real psychiatric and cardiac risks, and I would not recommend them to a patient with heart disease.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
LATE-STAGE HUMAN RESEARCH — Selected psychiatric conditions: promising supervised protocols; authorization and access remain jurisdiction-specific.Evidence grade (draft mapping)Grade pendingPart 22, Q330 · Part sources
All of Part 22

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