Question 323 of 433
Is it safe to get weight-loss injections from a med spa?

The short answer
Be very careful. Many are selling compounded copies whose legal basis ended when the drug shortages ended, and dosing mistakes have put people in the hospital.
During the shortages, pharmacies were allowed to compound semaglutide and tirzepatide. The FDA declared those shortages over in late 2024 and early 2025. Since then it has sent waves of warning letters to sellers and reported patients who injected five to twenty times the intended dose because they misread a multi-dose vial. Some products use salt forms of the drug that were never approved.
If you need one of these medicines, get the approved product through a physician who will check your labs, your muscle, and your plan for the long term. As for “lipotropic” and B12 “skinny shots,” no trial shows they cause fat loss.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
REGULATORY / SAFETY GUIDANCE — GLP-1 products: approved therapy differs from unapproved copies; lawful compounding is circumstance-specific.Evidence grade (draft mapping)RRegulatory statusPart 21, Q323 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.