Longevity UnmaskedLongevity Unmasked

Question 310 of 433

Is methylene blue safe to take for energy and focus?

Evidence grade (draft mapping)BLimited or small human studies
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The short answer

It is a real drug with real interactions, and the evidence for brain benefits is thin.

Methylene blue is an old dye, FDA approved only as an intravenous treatment for a rare blood disorder. It became popular online for mental energy. One small study showed slightly better memory after a single dose; others showed nothing.

The dangers are specific. It can cause a life-threatening reaction called serotonin syndrome when combined with common antidepressants. It destroys red blood cells in people with G6PD deficiency. It should not be used in pregnancy. Products sold as supplements have no dose or purity control.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
LIMITED COGNITIVE DATA / ESTABLISHED DRUG RISKS — Methylene blue for healthy focus; important interactions and contraindications.Evidence grade (draft mapping)BLimited or small human studiesPart 20, Q310 · Part sources
All of Part 20

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