Question 298 of 433
And the rest: MOTS-c, epitalon, thymosin alpha-1, GHK-Cu, semax?
The short answer
Interesting laboratory science, almost no human trials.
MOTS-c is a mitochondrial signal that improves metabolism in mice.
Epitalon is claimed to lengthen telomeres, based mostly on older Russian research.
Thymosin alpha-1 affects immune function and is approved in some countries for hepatitis, not in the United States.
GHK-Cu is a copper peptide. In skin creams it is reasonable; injected, it is untested.
Semax and selank are nasal peptides used in Russia for thinking and anxiety.
Each has a plausible story. None has the trials that would let a doctor tell you the right dose, the benefit, or the long-term risk.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
PRECLINICAL / LIMITED HUMAN — Named experimental peptides: no established general wellness benefit or standardized safe regimen.Evidence grade (draft mapping)DPreclinical / mechanisticPart 20, Q298 · Sources: R12
Sources cited
- R12 US Food and Drug Administration. Pharmacy Compounding Advisory Committee meeting materials, July 23–24, 2026. Link pending verification
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.