Longevity UnmaskedLongevity Unmasked

Question 295 of 433

What are peptides, and why is everyone talking about them?

Evidence grade (draft mapping)BLimited or small human studies
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The short answer

Short chains of amino acids that act as signals in the body. Some are excellent approved medicines. Most of the ones sold for healing and anti-aging have never been properly tested in people.

Insulin is a peptide. So are the GLP-1 medicines. So are two approved drugs you may hear about: tesamorelin, approved for abdominal fat in people with HIV, and bremelanotide, approved for low sexual desire in premenopausal women.

The peptides in the wellness market are different. They are sold on the strength of animal studies, athlete testimonials, and podcasts. They are usually injected.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
MIXED — Approved peptide drugs have indication-specific trials; wellness peptides do not inherit that evidence.Evidence grade (draft mapping)BLimited or small human studiesPart 20, Q295 · Sources: R12

Sources cited

  • R12 US Food and Drug Administration. Pharmacy Compounding Advisory Committee meeting materials, July 23–24, 2026. Link pending verification
All of Part 20

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