Question 238 of 433
How should I decide what to take?

The short answer
Test, correct what is low, add only what has human evidence for your specific goal, and review the list once a year.
Here is how the rest of this part is organized:
Tier 1: Worth taking for many people. Creatine, vitamin D if low, omega-3s for some, magnesium if your diet is short, B12 if you are at risk, and perhaps a basic multivitamin after 60.
Tier 2: Reasonable for specific goals. Urolithin A, glycine with NAC, CoQ10, psyllium fiber.
Tier 3: Biology ahead of benefit. NAD boosters, spermidine, curcumin, taurine.
Tier 4: Save your money. Resveratrol, most “telomere” and “stem cell” pills, proprietary blends.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
CLINICAL DECISION FRAMEWORK — Supplement use requires an indication; tiers are not a tested combined regimen.Evidence grade (draft mapping)JClinical judgment / author synthesisPart 17, Q238 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.