Question 217 of 433
Are DHEA and pregnenolone useful?
The short answer
Not for most people. Trials of DHEA in older adults showed little or no benefit for strength, body composition, or well-being.
They are hormones sold as supplements, which means little quality control. Vaginal DHEA is an approved prescription for a specific menopause symptom; that is a different product and purpose.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
HUMAN TRIALS — Older adults: DHEA shows little consistent general benefit; prescription vaginal DHEA has a separate indication.Evidence grade (draft mapping)Grade pendingPart 15, Q217 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.