Longevity UnmaskedLongevity Unmasked

Question 209 of 433

What are the risks, and what needs monitoring?

Evidence grade (draft mapping)ARobust human trials
Blood tube in a rack in an airy lab

The short answer

Thicker blood, infertility, worsened sleep apnea, acne, breast tenderness, and shrinking of the testicles. It requires regular blood tests.

Blood count. Testosterone raises red blood cells. Too many makes blood sluggish and may raise clot risk. This is the most common reason doses must be lowered.

PSA and prostate exam, as for any man of screening age.

Testosterone level, to keep it in the normal range and not above.

Sleep apnea, which should be tested and treated first.

As a cardiologist I add one caution of my own: the reassuring heart data apply to normal replacement doses in men with real deficiency. They do not apply to the high doses used for bodybuilding, which enlarge the heart, raise blood pressure, lower HDL cholesterol, and speed up plaque.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ROBUST SAFETY EVIDENCE — Testosterone-treated men: hematocrit, fertility, and other monitoring; individual contraindications matter.Evidence grade (draft mapping)ARobust human trialsPart 15, Q209 · Part sources
All of Part 15

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