Longevity UnmaskedLongevity Unmasked

Question 66 of 433

Do I need a “full” thyroid panel with reverse T3 and antibodies?

Evidence grade (draft mapping)GGuideline-based / consensus
Blood sample tubes and lab equipment in navy and gold light

The short answer

SKIP it unless your TSH is abnormal or you have clear symptoms. TSH first is the right approach.

Reverse T3 has no validated use in ordinary practice. Thyroid antibodies can predict future underactivity but rarely change what is done while the TSH is normal. “Optimal” TSH ranges narrower than the laboratory’s are not supported by outcome evidence. I have, in the past, written about tighter targets; the evidence has not borne them out, and I no longer chase them.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
GUIDELINE-BASED — Suspected thyroid disease: TSH-led assessment; routine reverse-T3 optimization is unsupported.Evidence grade (draft mapping)GGuideline-based / consensusPart 5, Q66 · Part sources
All of Part 5

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