Longevity UnmaskedLongevity Unmasked

Question 360 of 433

Does the immune system age?

Evidence grade (draft mapping)EEstablished clinical knowledge
Fermented foods, beans and berries on a sunny table

The short answer

Yes. With age we make fewer fresh immune cells, respond less to vaccines and new infections, and clear abnormal cells less well.

The thymus, the gland that trains T cells, shrinks to mostly fat by middle age. Dr. Topol argues that immune aging is a central driver of the diseases of aging, and the evidence is growing. What preserves immune function is familiar: exercise, sleep, adequate protein and vitamin D, low stress, and vaccination, which gives an older immune system a head start.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ESTABLISHED BIOLOGY — Immune aging; no single supplement or protocol reverses it clinically.Evidence grade (draft mapping)EEstablished clinical knowledgePart 24, Q360 · Part sources
All of Part 24

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