Longevity UnmaskedLongevity Unmasked

Question 355 of 433

What is the microbiome, and does it affect aging?

Sealed specimen kit on navy

The short answer

It is the trillions of bacteria living in your gut. They digest fiber, train the immune system, and produce chemicals that affect the whole body. Their balance shifts with age, and that shift is now counted as a hallmark of aging.

Healthy older adults and centenarians tend to have more diverse gut bacteria. Whether that diversity is a cause of their health or a result of it is not settled. Transferring gut bacteria from young to old animals has improved their health in experiments, which is suggestive.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
OBSERVATIONAL / PRECLINICAL — Microbiome patterns and aging; healthy diversity is not a universal treatment target.Evidence grade (draft mapping)CObservationalPart 24, Q355 · Part sources
All of Part 24

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