Longevity UnmaskedLongevity Unmasked

Question 346 of 433

Are personalized nutrition programs and DNA diets worth it?

Empty reclining therapy chair with blanket in dim navy room

The short answer

Coaching helps. The personalization itself has not been shown to matter much, and diets matched to your DNA do not work better than diets that are not.

A trial of one well-known program that uses glucose monitoring, stool testing, and an app found modest improvements in weight, waist, and triglycerides over 18 weeks compared with a leaflet of standard advice. LDL cholesterol did not improve. The trial could not separate the effect of the testing from the effect of having a coach and an app.

In a Stanford study of 609 people, genetic patterns did not predict who lost more weight on low-fat or low-carbohydrate diets. Eat like your grandmother, not like a lab.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
HUMAN TRIALS — Coaching packages can change markers; added benefit of proprietary testing or genotype matching is uncertain.Evidence grade (draft mapping)Grade pendingPart 22, Q346 · Part sources
All of Part 22

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