Question 270 of 433
Which medicines already qualify as proven longevity drugs?
The short answer
The ones that lower blood pressure and LDL cholesterol. They are so familiar that nobody thinks of them as longevity medicine, and they have added more years of life than everything else in this part combined.
Blood pressure medicines cut strokes by about a third and heart failure by half in people with hypertension, and protect against dementia.
Statins reduce heart attacks and strokes by roughly a fifth for each 40-point drop in LDL, with benefit growing the longer they are taken.
A combination “polypill” of low doses of these drugs was tested in a large trial in rural Iran. Over five years it reduced major heart events by about a third.
If you are searching for an anti-aging drug and have untreated high blood pressure, you have already found it.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
ROBUST HUMAN TRIALS — Indicated hypertension or lipid-risk populations: cardiovascular prevention; benefits are not uniform across all adults.Evidence grade (draft mapping)ARobust human trialsPart 19, Q270 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.