Question 252 of 433
Resveratrol was the original longevity supplement. What happened?
The short answer
It failed. It did not extend life in normal mice, human trials were disappointing, and the drug company that bought the idea abandoned it.
I mention it as a lesson. In 2006 resveratrol was on magazine covers and a red-wine pill seemed inevitable. Twenty years later it survives mainly on supplement shelves. Remember it whenever today’s miracle molecule is announced.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
NEGATIVE / INCONSISTENT — Resveratrol: normal-mouse lifespan and clinical outcomes have not supported the marketed longevity promise.Evidence grade (draft mapping)FNot demonstrated / insufficientPart 17, Q252 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.