Longevity UnmaskedLongevity Unmasked

Question 232 of 433

What is overdiagnosis?

Evidence grade (draft mapping)ARobust human trials
Low-dose CT room in daylight, empty

The short answer

Finding a “cancer” that would never have caused harm in your lifetime, and treating it anyway.

When South Korea began screening widely for thyroid cancer with ultrasound, diagnoses rose fifteen-fold. Deaths from thyroid cancer did not change. Tens of thousands of people had surgery and lifelong medication for tumors that would never have troubled them. The same happens to a lesser degree with some prostate and breast findings.

This is why more testing is not automatically better, and why I ask of every scan: if it finds something, will acting on it help this person?

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
ROBUST SCREENING EVIDENCE — Overdiagnosis can cause harm; its frequency depends on cancer type and population.Evidence grade (draft mapping)ARobust human trialsPart 16, Q232 · Part sources
All of Part 16

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