Longevity UnmaskedLongevity Unmasked

Question 190 of 433

What causes a hot flash, and how long do they last?

Evidence grade (draft mapping)DPreclinical / mechanistic
Plain cream tube with applicator on a white bathroom shelf in daylight

The short answer

Falling estrogen disturbs the brain’s thermostat, so the body suddenly acts as if it were overheating. On average, hot flashes last about seven years, and for some women more than ten.

Scientists have identified the specific nerve cells in the hypothalamus that misfire. That discovery led directly to new non-hormonal medicines that calm them. About three out of four women have hot flashes, and for roughly one in four they are severe enough to disrupt work and sleep.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
MECHANISTIC / HUMAN STUDIES — Vasomotor symptoms: thermoregulatory pathways and variable duration.Evidence grade (draft mapping)DPreclinical / mechanisticPart 14, Q190 · Part sources
All of Part 14

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