Longevity UnmaskedLongevity Unmasked

Question 70 of 433

IGF-1, uric acid, cystatin C, and GGT?

Evidence grade (draft mapping)GGuideline-based / consensus
MRI scanner bore in a dim navy room with gold accent light

The short answer

One of the four is clearly useful.

Cystatin C: WORTH IT in the right person. It gives a truer reading of kidney function when the usual creatinine test is distorted, as it is in very muscular people, frail people, and anyone taking creatine.

Uric acid: useful for gout. Treating a high level without symptoms has not been shown to help.

IGF-1: used to diagnose growth hormone disorders. Both low and high levels are linked to higher mortality, so there is no “optimal” target.

GGT: a nonspecific liver and alcohol marker.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
GUIDELINE / VALIDATION — Selected patients: cystatin C refines kidney assessment; the other markers require specific indications.Evidence grade (draft mapping)GGuideline-based / consensusPart 5, Q70 · Part sources
All of Part 5

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