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Question 81 of 433

What is pharmacogenomic testing?

Cheek swab kit with plain tubes on a white counter in daylight

The short answer

A test of how your genes affect your response to certain drugs. SOMETIMES, and most useful when you are about to start one of those drugs.

In a European trial, testing twelve genes before prescribing reduced serious side effects by about 30 percent. For a cardiologist the most relevant examples are clopidogrel, which does not work well in people with a particular gene variant, and statins, where one gene raises the chance of muscle aches. The test is done once and lasts a lifetime.

“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer

Evidence scope
HUMAN TRIAL — Selected drug–gene pairs: genotype-guided prescribing reduced clinically relevant adverse reactions.Evidence grade (draft mapping)Grade pendingPart 5, Q81 · Part sources
All of Part 5

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