Question 45 of 433
Which clock is the best?
The short answer
For predicting who gets sick and who dies, GrimAge and DunedinPACE perform best in research. No clock is yet good enough to steer treatment for one individual.
This distinction matters. In a study of thousands of people, a clock can clearly separate the fast agers from the slow. For one person on one day, the result can wobble by a couple of years depending on the lab, the time of day, a recent infection, or plain statistical noise.
“This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship.” From the book’s medical disclaimer. Full disclaimer
COMPARATIVE RESEARCH — Different clocks estimate different constructs; no best clinical treatment-guidance clock established.Evidence grade (draft mapping)Grade pendingPart 4, Q45 · Part sources
From Longevity Unmasked by Afshine Ash Emrani, MD, FACC. Medical disclaimer. This book is for education. It is not medical advice, and reading it does not make you my patient or create a doctor-patient relationship. Nothing here is meant to diagnose, treat, cure, or prevent any disease. Medicine is personal: a test, drug, supplement, or exercise plan that helps one person can harm another. Do not start, stop, or change any medication or treatment because of something you read in these pages. Talk with a licensed clinician who knows your history first. If you think you are having a medical emergency, call 911. The author disclaims responsibility for any loss or harm arising from use of the information in this book.